Compartmentalized DCC signalling is distinct from DCC localized to lipid rafts
نویسندگان
چکیده
منابع مشابه
DCC association with lipid rafts is required for netrin-1-mediated axon guidance.
During development, axons migrate long distances in responses to attractive or repulsive signals that are detected by their growth cones. One of these signals is mediated by netrin-1, a diffusible laminin-related molecule that both attracts and repels growth cones via interaction with its receptor DCC (deleted in colorectal cancer). Here we show that DCC in both commissural neurons and immortal...
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ژورنال
عنوان ژورنال: Biology of the Cell
سال: 2009
ISSN: 0248-4900
DOI: 10.1042/bc20070108